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Human T cells play a central role in the human response to tuberculosis and in efforts to develop better vaccines. For decades, it was thought that T cells only that recognize antigens in the context of a diverse array of presentation molecules such that an epitope could be considered private, or restricted to each patient or human donor. Therefore, broad detection or alteration of T cell responses to one kind of antigen in all humans was viewed as technologically impossible. Over the past decade “Donor Unrestricted T cells” (DURT) that recognize their antigens through highly conserved molecules that are present among all humans have been discovered. The CTVD DURT research community seeks to harness these donor unrestricted T cell responses to MR1, CD1 and HLA-E proteins for improved vaccines against TB.

The DURT research community is comprised of individuals from different Institutions worldwide and includes the following members:​​

Dave Lewinsohn   Co-chair
Branch Moody Co-chair
John Altman Member
Sam Behar Member
Yueh-hsiu Chien Member
Dan Hoft Member
Simone Joosten Member
Tom Ottenhoff Member
Louis Picker Member
Ann Rawkins Member
Jonah Sacha Member
Tom Scriba Member
Chetan Seshadri Member
Sally Sharpe Member
Emmanuel   Treiner Member
Ildiko Van Rhijn Member